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Oct 31, 2024
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BINF 6205 - Computational Molecular Evolution Covers major aspects of molecular evolution and phylogenetics with an emphasis on the modeling and computational aspects of the fields. Topics will include: models of nucleotide substitution, models of amino acid and codon substitution, phylogenetic reconstruction, maximum likelihood methods, Bayesian methods, comparison of phylogenetic methods and tests on trees, neutral and adaptive evolution and simulating molecular evolution. Students will obtain an in-depth knowledge of the various models of evolutionary processes, a conceptual understanding of the methods associated with phylogenetic reconstruction and testing of those methods and develop an ability to take a data-set and address fundamental questions with respect to genome evolution.
Credit Hours: (3) Prerequisite(s): BINF 6201 and BINF 6200 or permission of instructor.
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