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Oct 31, 2024
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BINF 8201 - Molecular Sequence Analysis Introduction of the basic computational methods and open sources software commonly used in molecular sequence analysis. Topics include: biological sequence data formats and major public databases, concepts of computer algorithms and complexity, introductions to principle components analysis and data clustering methods, dynamics of genes in populations, evolutionary models of DNA and protein sequences, derivation of amino acid substitution matrices, algorithms for pairwise sequence alignments and multiple sequence alignments, algorithms for fast sequence database search, methods for molecular phylogenetic analysis, hidden Markov models and neural networks for sequence pattern and family recognition, and introductions to genome evolution and comics data analysis.
Credit Hours: (3) Prerequisite(s): BINF 8100 or equivalent.
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