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Dec 30, 2024
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BINF 8205 - Computational Molecular Evolution Major aspects of molecular evolution and phylogenetics with an emphasis on the modeling and computational aspects of the fields. Topics include: models of nucleotide substitution, models of amino acid and codon substitution, phylogenetic reconstruction, maximum likelihood methods, Bayesian methods, comparison of phylogenetic methods and tests on trees, neutral and adaptive evolution and simulating molecular evolution. Students obtain an in-depth knowledge of the various models of evolutionary processes, a conceptual understanding of the methods associated with phylogenetic reconstruction and testing of those methods and develop an ability to take a data-set and address fundamental questions with respect to genome evolution.
Credit Hours: (3) Prerequisite(s): BINF 8200 and BINF 8201 , or permission of instructor.
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